Estradiol (E2)
- C1089
Rs 594
- Why Get Tested?
Estrogens; Estrone; Estradiol; Estriol - When To Get Tested?
To measure or monitor your estrogen levels; to detect an abnormal level or hormone imbalance as a cause of your signs and symptoms; to monitor treatment for infertility or symptoms of menopause; sometimes to test for fetal-placental status during early stages of pregnancy - Sample Type:SERUM (SST or Plain)
- Fasting :AS PER DOCTOR
- Report Delivery:within 48 Hrs of Test Schdule
- Components:1 Observations
- Also Known As:
Estrogens - Formal Name:
Estrogen Fractions/fractionated Estrone (E1) Estradiol (E2) Estriol (E3) Estrogenic Hormones - Sample Instructions:
To measure or monitor your estrogen levels; to detect an abnormal level or hormone imbalance as a cause of your signs and symptoms; to monitor treatment for infertility or symptoms of menopause; sometimes to test for fetal-placental status during early stages of pregnancy When To Get Tested? Women: when you show symptoms of a hormone imbalance, such as abnormal vaginal bleeding, lack of menstrual periods, unusual and/or early or late sex organ development; when you are undergoing infertility treatment or therapy for menopause symptoms; when you are pregnant and your health practitioner wants to monitor the health of your placenta and developing baby, if it is a high-risk pregnancy Men: when you have signs of feminization, such as enlarged breasts (gynecomastia) - Test Preparation Needed?
A blood sample drawn from a vein in your arm or a 24-hour urine sample - What Is Being Tested?
None - How Is It Used?
Estrogens are a group of steroids that are responsible for the development and function of reproductive organs and the formation of secondary sex characteristics in women. Along with another hormone, progesterone, they help regulate the menstrual cycle, are involved in the growth of breasts and the uterus, and help maintain a healthy pregnancy. Though considered the main sex hormones for women, they are also found in men and play a role in bone metabolism and growth in both sexes. Estrogen tests measure one of three components: estrone (E1), estradiol (E2), or estriol (E3) in the blood or urine. Estrone (E1) is directly converted from androstenedione (from the adrenal gland) or indirectly from other androgens. E1 can also be produced by the ovaries and placenta, testicles, and adipose (fat) tissues. E2 and E1 can be converted into each other as needed. E1 is the primary estrogen in men and in post-menopausal women. Estradiol (E2) is primarily produced in the ovaries in pre-menopausal women and in the testicles in men. E2 is converted from E1 in post-menopausal women. It is the most potent estrogen and the one that is present in the highest concentration in non-pregnant, pre-menopausal women. E2 levels vary depending on a woman's age and reproductive status. They are a good marker of ovarian function. Estriol (E3) is produced by the placenta, with concentrations rising throughout a woman's pregnancy. Increasing levels are an indication of the health of the pregnancy and developing baby. Estriol is part of the second trimester maternal serum screen, a test performed to evaluate fetal risk due to certain chromosomal abnormalities. Very low levels of E3 are present in non-pregnant women or men. Estrogen in Girls and Women The types and amounts of estrogen normally present in a woman's blood will vary throughout her lifetime. Levels vary during each menstrual cycle, during pregnancy, and on a daily basis. At Birth Estradiol (E2) and estrone (E1) are high b - When Is It Ordered
Estrogen tests are used to detect a deficiency or excess in a woman and to help diagnose a variety of conditions associated with this imbalance. They may also be used to help determine the timing of a woman's ovulation and may be ordered to monitor the health status of the developing baby and placenta during pregnancy. In a man, estrogen testing may be performed to detect a hormone excess and its cause. Estrogen tests measure one of three components: estrone (E1), estradiol (E2), or estriol (E3). These tests each have different uses. In Girls and Women Estradiol (E2) and/or estrone (E1) testing may be ordered to: Help diagnose early-onset puberty, when a young girl develops secondary sex characteristics sooner than expected; or delayed puberty, when a girl shows delayed development of secondary sex characteristics or start of menstruation Investigate menstrual abnormalities, such as lack of menstrual periods (amenorrhea), infertility, and abnormal vaginal bleeding Evaluate the function of the ovaries and detect ovarian failure Monitor follicle development in the ovary in the days prior to in vitro fertilization by making serial measurements of estradiol Monitor hormone replacement therapy that is given to assist fertility Monitor menopausal hormone replacement therapy that is given to alleviate symptoms associated with estrogen deficiency Detect estrogen-producing tumors Monitor anti-estrogen therapy, as in breast cancer Estriol (E3) testing: May sometimes be ordered serially to help monitor a high-risk pregnancy; when it is used this way, each sample should be drawn at the same time each day. An unconjugated estriol test is one of the components of second trimester maternal serum screening. Decreased levels have been associated with various genetic disorders, including Down syndrome, neural tube defects, and adrenal abnormalities. In Boys and Men Estradiol (E2) and/or estrone (E1) testing in boys or men may be ordered - What Does The Test Result Mean?
In Girls and Women Estradiol (E2) and/or estrone (E1) testing in girls and women may be ordered when: A girl's sex organs develop earlier or later than normally expected A woman has symptoms such as abnormal vaginal bleeding after menopause or abnormal or lack of menstrual cycles A woman is experiencing infertility; a series of estradiol measurements over the course of a woman's menstrual cycle may be done to monitor follicle development prior to in vitro fertilization techniques (timed with a surge in estradiol). A woman is having symptoms of menopause, including hot flashes, night sweats, insomnia, and/or irregular or lack of menstrual periods A menopausal woman is taking hormone replacement therapy; her health practitioner may periodically order estrone levels to monitor treatment. Estriol (E3) testing in women may be ordered: During pregnancy, a health practitioner may order serial estriol samples to look for a trend, whether there is a rise or fall in the estriol level over time. Unconjugated estriol is often measured in the 15th to 20th week of gestation as part of the triple/quad screen. In Boys and Men Estradiol (E2) and/or estrone (E1) testing in boys and men may be ordered when: A boy has delayed puberty, characterized by delayed development of muscle mass, lack of deepening of the voice or growth of body hair, slow or delayed growth of testicles and penis A man shows signs of feminization, such as enlarged breasts - Is There Anything Else I Should Known?
Normal estrogen results depend upon the sex and age of the person being tested. With women, it also depends upon their menstrual cycle or whether they are pregnant. Reference ranges will vary somewhat between laboratories, both in normal values listed and in units used. Increased or decreased levels of estrogens are seen in many metabolic conditions. Care must be used in the interpretation of estrone, estradiol, and estriol results because the levels vary on a day-to-day basis and throughout a woman's menstrual cycle. A health practitioner who is monitoring a woman's hormones will be looking at trends in the levels, rising or lowering over time in conjunction with the menstrual cycle or pregnancy rather than evaluating single values. Test results are not diagnostic of a specific condition but give the health practitioner information about the potential cause of a person's symptoms or status. Below are conditions with which one might see an increase or decrease of estrogen levels. Increased levels of estradiol (E2) or estrone (E1) are seen in: Girls and Women: Early (precocious) puberty Tumors of the ovary or adrenal glands Boys and Men: Enlarged breasts (gynecomastia) Tumors of the testicles (testicular cancer) or adrenal glands Delayed puberty Both Women and Men: Hyperthyroidism Cirrhosis In women, decreased levels of estrogen are seen in: Turner syndrome, an inherited condition in women caused by a missing or abnormal X chromosome and characterized by underdeveloped female sex characteristics Low level of pituitary hormones (hypopituitarism) Dysfunction of the ovaries (female hypogonadism) Failing pregnancy (estriol) Eating disorders such as anorexia nervosa After menopause (estradiol) PCOS (Polycystic ovarian syndrome, Stein-Levanthal syndrome) Extreme endurance exercise
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